The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging
CHEN Yi-Yong, YIN Wei-Gang, LIN Rong, WANG Shou-Dao, HONG Hai-Qing, LI Lin
Chinese Journal of Clinical Anatomy ›› 2014, Vol. 32 ›› Issue (1) : 36-40.
The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging
Objective To show the fibers that connected the cerebellum with brainstem, diencephalon and spinal cord using GQI. Methods We acquired high-resolution structural and diffusion MRI of 10 subjects from HCP. The tractography based on a GQI and streamline algorithm of the DSI-studio software was performed to reconstruct and show the fibers that linked the cerebellum with other parts of the CNS(Central Nervous System). Results (1) 2-dimensional and 3-dimensional positions and intersections of the superior (SCP), and middle (MCP) and inferior (ICP) cerebellar peduncles were showed using the DSI-studio software. (2) the main ingredients of the three peduncles of cerebellum which connected to the spinal cord, medulla oblongata, pons, midbrain, diencephalon were 3-dimensionally demonstrated. Conclusions The cerebellum medulla can reconstructed and displayed using GQI, providing a diagnostic tool for characterizing anatomical disruptions that occur in cerebellar diseases and for monitoring response to therapeutic interventions.
Generalized Q-sampling Imaging(GQI) / Human Connectome Project(HCP) / DSI-studio software / Medulla of cerebellum
[1] Schmahmann JD, Sherman JC. The cerebellar cognitive affective syndrome
[J]. Brain, 1998,121 ( Pt 4): 561-579.
[2] Schmahmann JD, Weilburg JB, Sherman JC, et al. The neuropsychiatry of the cerebellum -insights from the clinic
[J]. Cerebellum, 2007,6(3):254-267.
[3] Salamon N, Sicotte N, Drain A, et al. White matter fiber tractography and color mapping of the normal human cerebellum with diffusion tensor imaging
[J]. J Neuroradiol, 2007,34(2):115-128.
[4] Leuze CW, Anwander A, Bazin PL, et al. Layer-Specific Intracortical Connectivity Revealed with Diffusion MRI
[J]. Cereb Cortex, 2012.
[5] Wedeen VJ, Rosene DL, Wang R, et al. The geometric structure of the brain fiber pathways
[J]. Science, 2012,335(6076):1628-1634.
[6] Tuch DS, Wisco JJ, Khachaturian MH, et al. Q-ball imaging of macaque white matter architecture
[J]. Philos Trans R Soc Lond B Biol Sci, 2005,360(1457):869-879.
[7] Wedeen VJ, Wang RP, Schmahmann JD, et al. Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers
[J]. Neuroimage, 2008,41(4):1267-1277.
[8] Fang-Cheng Yeh VJW, Wen-Yih Isaac Tseng, et al. Generalized Q-Sampling Imaging
[J]. IEEE Trans Med Imaging, 2010,27: 1415-1424.
[9] Wakana S, Jiang H, Nagae-Poetscher LM, et al. Fiber tract-based atlas of human white matter anatomy
[J]. Radiology, 2004,230(1):77-87.
[10] Strick PL, Dum RP, Fiez JA et al. Cerebellum and nonmotor function
[J]. Annu Rev Neurosci, 2009,32 413-434.
[11] Cantalupo C, Hopkins W, et al. The cerebellum and its contribution to complex tasks in higher primates: a comparative perspective
[J]. Cortex, 2010,46(7):821-830.
[12] Stoodley CJ, Schmahmann JD. Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processing
[J]. Cortex, 2010,46(7):831-844.
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